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Methionine biosynthesis occurs in three consecutive reactions catalyzed by cystathionine -synthase (CGS), cystathionine -lyase (CBL), and methionine synthases (MS) (Ravanel et al., 1998b)

Water retention: Slight puffiness in the hands or feet, most common during the escalation phase and typically self-limiting

This approach forces a difficult decision between temporary relief and an invasive, end-stage procedure

Speculatively, a certain basal level of tissue DHT may actually be required to help maintain the AR steady state content in the penis

doi: 10.1038/nm.4106

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