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Collagen remodeling takes time (a fibroblast doesn't build new collagen overnight), so this is the window where visible skin firmness, texture, and hair density improvements become most noticeable

This effect is useful for both people with diabetes and those at risk for it, especially those who are overweight

Wang et al., 2019a)

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GLP-1 agonists, such as semaglutide or tirzepatide, act on the GLP-1 receptor to suppress appetite and to regulate glycemia