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Nature of T cell epitopes in lupus antigens and HLA-DR determines autoantibody initiation and diversification

It supports the regeneration of other antioxidants, such as vitamins C and E, enhancing the body's overall antioxidant capacity

doi: 10.1016/S1360-1385(03)00053-0 43 Gomez-RoldanV.FermasS.BrewerP

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Variations in cohort characteristicsincluding age, BMI, and ethnic backgroundinconsistent application of diagnostic criteria, and unstandardized intervention protocols such as dose-duration ratios, combination therapies significantly limit the comparability of findings and obscure true effect sizes in existing meta-analyses

Non-oxidizable groups, such as CF3 or tert-butyl, at C3 or C7 improve metabolic stability, as demonstrated in mouse liver microsomes (Farmer et al., 2022)