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RCT conducted in patients with T2D showed that high doses of tirzepatide represent the most efficacious incretin-based anti-diabetes drug in terms of BW reduction 33 , sustaining the development of the SURMOUNT program to explore its efficacy and safety in the management of obesity 9

Mutations in CYP2U1, DDHD2 and GBA2 genes are rare causes of complicated forms of hereditary spastic paraparesis

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This article examines the mechanisms of B12 uptake, practical guidance on supplement timing, and the clinical factors that affect how quickly deficiency can be corrected