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Higher doses dont have any clinical basis and may increase risk

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There are also indications of an upregulation of ABCG2 in correlation with an inflammatory marker in human brain tissue 49

10.1016/j.tcb.2018.02.004 Trends Cell Biol

Yes, NAC is a glutathione precursor

have shown that Epithalon not only extends lifespan and reduces tumor incidence in animal models, but also decreases chromosomal aberrations, supporting its role in maintaining genetic stability and anti-aging effects