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10.3390/molecules28031233 [DOI] [PMC free article] [PubMed] [Google Scholar] Rifai, K

Tesamorelin (trans-3-hexenoic acid modified GHRH 1-44) is an FDA-approved GHRH analog with enhanced stability compared to native GHRH

VHL alterations in RCC cells lead to the activation of hypoxia-inducible factors and their downstream target vascular endothelial growth factor, and to the reprogramming of multiple cell death pathways and metabolic weakness, including ferroptosis, which are associated with targeted therapy or immunotherapy

doi: 10.1016/j.actbio.2010.08.016

Research-use disclaimer: This article is educational reference material summarizing published research and regulatory context