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When talking about its functional duration, it is worth mentioning that even after plasma concentrations decline, hormonal signaling effects may persist

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An exfoliating treatment or a face scrub can help, but only in moderation: Exfoliation can play a role in managing hyperpigmentation, she says, but there is a need to strike a balance, as excess exfoliation can also contribute to excess pigmentation. Finally, some ingredients, such as tranexamic acid and niacinamide , block the transfer of pigment from the pigment-producing cells to your skin cells

TABLE 1 Effects of Yang/Qi-invigorating formulations on the treatment of CKD