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Terenghi G, Riveros-Moreno V, Hudson LD, Ibrahim NB, Polak JM
Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts
[PubMed: 25088083] (35 year old Japanese woman developed acute liver injury first noted 14 days after a 2-day course of acetaminophen, cefcapene and loxoprofen which progressed to an acute icteric hepatitis 6 weeks later [peak bilirubin 8.2 mg/dL, ALT 659 U/L, prothrombin index 35%] with ascites and encephalopathy responding to corticosteroids, but ALT elevations persisting with positive lymphocyte stimulation test to acetaminophen only)
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It must not be administered to humans or animals outside strictly controlled, legally permitted research conditions
