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While pathological amyloids (and prions) emerge from protein misfolding, a class of functional amyloids has been defined, consisting of amyloid-forming domains under natural selection and with diverse biological roles

Key points Microplastics and nanoplastics (MNPs) are increasingly detected in human cardiovascular tissues, including blood, atherosclerotic plaques and myocardium, suggesting systemic distribution and potential involvement in cardiovascular disease pathogenesis

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