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Among these proteins, iron is not only responsible for oxygen transport and storage but also promotes oxygen metabolism through oxidases, peroxidases, and catalase, among others
Patients with certain medical conditions should be evaluated first
6 Conclusion In summary, increasing research evidence supports a key role for ferroptosis in the occurrence and progression of OA
This bidirectionality may explain why some nutrient interventions fail [e.g., vitamin B12 supplementation is ineffective in patients with gut microbiota dysbiosis (149)]
Adenosylcobalamin is another active form of vitamin B12