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Females of childbearing age, which make up approximately 50% of all Accutane users, must agree to monthly pregnancy tests and to use two forms of birth control while taking isotretinoin

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Every batch is analyzed by an independent, ISO 17025-accredited laboratory using HPLC and LC-MS testing to confirm identity and quantify purity

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Some practitioners implement cycling to theoretically prevent receptor desensitization, provide physiological breaks, or manage costs, though evidence supporting these approaches is limited

Di Monaco, M