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Massons trichrome stain and Immunohistochemistry presented that compared with COPD rats treated with NAC and oe-NC, collagen volume fraction and -SMA level increased in lung tissues of COPD rats treated with NAC and oe-VWF

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Consistent with this positive correlation between glutamine breakdown and mTORC1, FOXO-mediated GS expression inhibits mTOR signaling by blocking its lysosomal translocation