From structural point of view, protein complexes (or aggregates) behaving as prion-like entities could represent molecular assemblies of individually folded domains or strictly cooperative folds, like amyloids, where monomers contribute toward -sheet-rich folds by layering inside the same structures, extending into fibrillar macromolecular assemblies (amyloid fibers)
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Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk
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E., Van Den Bossche, J., Hoeksema, M