The basic science of articular cartilage: structure, composition, and function
The ALA/DHLA redox couple possesses a remarkable ability to regenerate and recycle other depleted endogenous antioxidants
The remedial potential of lycopene in pancreatitis through regulation of autophagy
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Cells with higher NAD+ are more metabolically active and burn more calories at rest
Ascorbate can be regenerated from its oxidized forms, monodehydroascorbate (MDHA) and dehydroascorbate (DHA), by MDHA and DHA reductases (MDHARs and DHARs), respectively (Smirnoff, 2018) The activity of DHARs is coupled to oxidation of glutathione, which is also required for spontaneous, non-enzymatic reduction of DHA to ascorbate (Figure 1)