Learn about the genetic variants that throw a caution flag on this one
Alternative Therapies in Health and Medicine , 12(4), 1223
Main text Exercise-induced stress response In sports, high metabolic stress followed by the short recovery period makes the athletes training routine exhaustive [47]
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Furthermore, ZLN005 treatment activates mitophagy, as manifested by increased expression of LC3-II and co-localization between LC3 and mitochondria, and the protective effects are abrogated in TFEB-knockdown cells, suggesting that PGC-1 activation improves mitochondrial dysfunction via TFEB-mediated autophagy
On the other hand, PGC-1/NRF1 regulates FUNDC1-mediated mitophagy through transcription, promoting mitochondrial biogenesis during the process of mitochondrial autophagy, accelerating mitochondrial turnover, and maintaining normal mitochondrial respiration and mitochondrial population stability