Systematic re-evaluation of the bis(2-hydroxyethyl)disulfide (HEDS) assay reveals an alternative mechanism and activity of glutaredoxins
some extend to 12 weeks with periodic breaks
Glutathione undergoes a reaction with the toxic substances, facilitated by enzymes such as glutathione S-transferases, to form a conjugate known as a glutathione adduct, which is then further metabolized in the liver to form mercapturic acid, a water-soluble compound that can be easily excreted through the urine
Differences in cohort, duration, and titration make a precise cross-trial advantage unreliable
About this article Cite this article Kishimoto, Y., Saita, E., Ohmori, R
Scientific References Bacteriostatic Water for Injection SmPC (EMC product 6655)