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10.1016/j.niox.2010.10.002 138

Table 1 Global Response Assessment Scale Number Response Grading (%) Outcome 1 Significantly worse 0 Failure of the therapy 2 Somewhat worse 1 to 25 Failure of the therapy 3 Unchanged (neither worse nor better) 26 to 50 Failure of the therapy 4 Somewhat improved 51 to 75 Successful therapy 5 Significantly improved 76 to 100 Successful therapy Inclusion criteria This study included patients with moderate to severe interstitial cystitis who had participated in the experimental trial conducted in January 2023 at the UroGyn Specialists of Florida clinic using the nonFDA-approved BPC-157 peptide

doi: 10.1258/ebm.2012.011416 73 WeiZWangFSongJLuQZhaoPXiaYet al

[DOI] [PMC free article] [PubMed] [Google Scholar] Sousa B

Croatian researchers first isolated and characterized this peptide in 1993 from a larger protein found naturally in human gastric juice

While a single-donor model is more comparable to an in vivo situation then a multi-donor model, single-donor cardiac MTs might be more susceptible for bias due to genotype sensitivity than our multi-donor hepatic MTs that have the ability to even out these effects