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Levels naturally decline over time due to age, stress, environmental exposure, and lifestyle factors

Yin Z, Albrecht J, Syversen T, Jiang H, Summar M, Rocha JBTda, Farina M, Aschner M (2009) Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-culture

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Severe or prolonged exercise can overwhelm antioxidant defences, which include vitamins E and C and thiol antioxidants, which are interlinked in an antioxidant network, as well as antioxidant enzymes

modulation by racial discrimination stress

That heavy blanket of tiredness that just wont lift, even after a good nights sleep