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Subsequently, we investigated the therapeutic potential of P-Mn/TI@mHSA in treating established atherosclerotic plaques
If these molecules accumulate, they can damage lipids, proteins, and DNA
In KRAS-mutated colon cancer cells, SLC25A22-mediated Gln breakdown reduces H3K4me3 methylation, stimulates the activation of the Wnt/beta-catenin signaling pathway, and diminishes the sensitivity of colon cancer cells to chemotherapeutic agents (35)
Gc t dol nguyn nhn hng u gy ra tn thng t bo, khin ADN v cc phn t protein b bin i
268,269 Recently, single-cell sequencing also confirmed the presence of a large number of mtDNA mutations in senescent cells, and more than 60% of the mutations occurred in protein-coding genes
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