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During ischemia, ATP release originates from multiple sources, such as vesicular release from neurons (Orlando et al., 2014), exocytosis from microglia (Imura et al., 2013) and astrocytes (Hamilton and Attwell, 2010), hemichannels that can release ATP from glial cells (Montero and Orellana, 2015), or by opening of P2X 7 ionotropic receptors that form a large pore allowing the ATP release from astrocytes (North, 2002

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Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer