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The peptide accelerates regeneration of intestinal mucosa and submucosa, restores tight junction proteins (claudin-1, occludin, ZO-1) that fail in intestinal permeability syndromes, and increases local blood supply through VEGF-mediated angiogenesis

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Compared to GHRP-2 (improved GHRP-6 evolution), Ipamorelin remains more selective: GHRP-2 still produces a slight prolactin increase and modest cortisol stimulation

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(PubMed) Stranges S, Marshall JR, Natarajan R, et al