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Additionally, iron-activated ERK/MAPK pathways may contribute to tau phosphorylation and neuroinflammatory cytokine release, suggesting a potential feedback loop between iron dysregulation, tau pathology, and inflammation (125, 126)

Research shows this mechanism gives insights into fat metabolism, muscle health and NAD+ biology

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EGb761 was shown to protect against dopaminergic neurotoxicity caused by MPTP whether it was given before or after the treatment (Sharma et al., 2019b)