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Linardopoulos, Aurora kinase inhibitors: current status and outlook

The variability in GSH levels depending on the stage of the disease makes it difficult to use GSH as an effective clinical trial biomarker to measure change

Blood 86(10):672a, 1995

Metabolic syndrome severity score and the progression of CKD

instead, they may help regulate the communication between them

This notion is confirmed by the observation that PARP1 and CD38 inhibition effectively increases total NAD + availability, leading to SIRT1 activation