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2018 Jun;233(6):4497-4511

In PAM212 cells, 12-hour closure was lower but still notable, achieving 87% (GHK-AgNPs) and 90% (GHK-Cu-AgNPs) at 24 hours, both significantly higher than controls

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There are speculations that non-pathogenic commensal microorganisms, which co-evolved with humans, have been a source of immunomodulatory signals for the human body (the old friends hypothesis), and now prevent the development of immune-mediated chronic diseases (the hygiene hypothesis), with the proper composition of the microbiome promoting the maintenance of the bodys immune balance (the biodiversity hypothesis) [1, 39, 53, 54]

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