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The nitric oxide generated through this pathway promotes vasodilation, inhibits platelet aggregation, and enhances endothelial cell survival while supporting the formation of patent, functional vessels

It does not cause the hormonal cascading effects that make compounds like DNP, T3, or high-dose growth hormone risky for long-term use

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Chang and colleagues (J Appl Physiol, 2011) documented enhanced tenocyte outgrowth, survival, and migration in cultured Achilles tendon preparations