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with Arg242 and Arg257 of VP1 from neighbouring protomers in the interface conferring strong positive charge characteristics to the GSH-binding pocket and forming hydrogen bond and saltbridge contacts with the carboxy terminus of GSH (Fig

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After 48 h, the samples were collected, observed under a microscope, and photographed

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MTX + MCP group: Rats were given MCP (200 mg/kg/day, orally for 14 days) and a single intraperitoneal MTX injection (40 mg/kg) on day 9