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In one study, mice treated with 20mg/kg of 5-amino-1mq three times daily for 11 days experienced a 5.1% reduction in body weight from baseline

This could be 1000 mcg daily or less, based on the patients needs

Li and Tang, 2020)

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is essential for nervous system function, red blood cell development, DNA synthesis, energy metabolism, and antioxidant activity

Thereby, the application of NO-agents, NOS-blockade L-NAME, NO-over-activity (L-arginine, NOS-substrate) and their relationships (opposite or parallel activities, mutual counteraction or not), which can cover all essential points of NO-system, and the full spectrum of NO-system functions was combined with BPC 157 application to show its full efficacy on maintaining and/or reestablishing NO-system effects and functions [124,125]

This is a genuinely difficult question to answer with intellectual honesty