58 Mitochondrial bioenergetics are also stimulated by the H 2 S-generating 3-MST substrate 3-MP (Table 1) both in the murine colon cancer CT26 cell line 147 and in mouse hepatoma cells, 148 where silencing of 3-MST or SQR decreased basal cellular bioenergetics, further suggesting that mitochondrial bioenergetics are partially sustained by SQR-mediated H 2 S oxidation (Table 1)
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Funding This work was supported by the National Natural Science Foundation of China (NSFC82173532, NSFCU20A20350, NSFC81971455, NSFC81871216 and NSFC81601345), the Excellent Young Talents Fund Program of Higher Education Institutions of Anhui Province (gxyq2021173), the Postdoctoral Research Foundation of China (2021M700181), the University Natural Science Research Project of Anhui Province (KJ2020A0203), the National Key Research and Development Program (2018YFC1004201, 2016YFC1000204)
