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The ultimate solubility of the negatively charged niclosamide salt (Nic -ve ) at pH 9.5 was 641uM

Clinical data were collected, and genotyping analysis was performed through a TaqMan assay

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These findings provide limited support for prior work suggesting sex-related variation in stimulant response and tolerability ( The current sample spanned a wide age range (778 years), which enhances generalizability, but also introduces developmental heterogeneity

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Introduction Systemic sclerosis (SSc) is a rare connective tissue disease characterized by immune dysregulation, vasculopathy, and progressive fibrosis affecting the skin and internal organs