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PMID: 245 ZhaoYShenMWuLYangHYaoYYangQet al

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Another principal function of the NADPH produced by ER-localized hexose-6-phosphate dehydrogenase is to provide the reducing energy to ER-localized reductases, specifically those involved in steroid hormone metabolism, with 11-hydroxysteroid dehydrogenase 1 (11-HSD1

doi: 10.2174/13816128130111

407 Notably, TRIM11 promotes proteasomal degradation of tau while simultaneously acting as a molecular chaperone that suppresses tau misfolding