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672,673 DFO treatment significantly reduces iron accumulation in brain tissue and BMECs, increases brain capillary density, and improves cerebral blood flow and behavioral performance

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Other histological changes, including portal inflammation, polymorphonuclear infiltrates, MalloryDenk bodies, apoptotic bodies, clear vacuolated nuclei, microvacuolar steatosis, and megamitochondria, can be seen in NASH, but are not necessary for the diagnosis

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