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The presence of GSH could inhibit the peroxidase-like activity of CS-AuNPs, thereby reducing the formation of oxTMB

The study by Honda et al., conducted in 2017, was an open-label, single-arm, multicentre pilot study that evaluated the therapeutic effect of oral glutathione administration (300 mg/day) in patients with NAFLD through the evolution of biochemical indices (ALT) and liver fat levels assessed by VCTE (79)

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As described above, sulforaphane modifies cysteine residues within the KEAP1 ubiquitin ligase, albeit distinct cysteine residues from those that become oxidized by ROS (Suzuki et al., 2019)

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