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The prime constituent of R

5.2 TCM compound Derived from Ye Tianshis Secret Formulas for Gynecological Syndromes, Wenshen Tiaojing Decoction was shown to significantly decrease oxidative stress markers and downregulate ferroptosis-related genes in a PCOS mouse model (104)

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The peptide's interaction with dopaminergic and serotonergic neurotransmitter systems extends its mechanism into the nervous system, connecting each biological action directly to a documented benefit across multiple tissue types

However, this effect is largely eliminated by lowering Ero1 function through RNA interference, indicating that Ero1 activity in vivo leads to the production of ROS