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Current evidence suggests that the adverse effects sometimes associated with taurine are due to the use of large amounts of stimulants in combination with alcohol and/or intense physical exercise

Hamrang-Yousefi S, Ng J, Andaloro C

doi: 10.1016/j.plefa.2003.08.010 53 PatelSSharmaDKaliaKTiwariV

NAD + can be generated de novo in the kynurenine pathway, where Trp is oxygenated to N-formylkynurenine by tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO) 31

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The observation that BPC-157 appears to activate this pathway (via phosphorylation of FAK and paxillin) in cultured fibroblasts provides a direct molecular explanation for how it might accelerate wound closure and tissue repair in research models