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Importantly, with time the majority of relapse-onset patients will transition to a clinically progressive course [known as secondary progressive MS (SPMS)] characterized by cytodegeneration, while the inflammatory component wanes with age (Compston and Coles, 2008)

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C.et al (2013)

what about if the pt came in for Prolieve (CPT 53850) that has a 90 day global period, who also received a gentamicin injection (96372 w/ J1580) at the time of the procedure

Regular monitoring of serum copper and ceruloplasmin levels may be warranted for long-term users, particularly those exceeding recommended dosages