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Collectively, NAC is a powerful anti-inflammatory and antioxidant agent that can be used in a wide variety of disease states

Researchers should not treat them as substitutes for each other based solely on their shared appearance in tissue-repair literature

Furthermore, administering certain microbial metabolites to mice, such as urolithin A, can enhance barrier function by upregulating AhR and nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent signaling 98

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Another analysis of 12 studies found that people who took alpha-lipoic acid lost an average of 2.8 pounds (1.27 kg) more than those taking a placebo over an average of 23 weeks ( In short, it seems that alpha-lipoic acid has just a slight effect on weight loss in humans