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In general, the mitochondrial reduced:oxidised ratio is greater than that of the cytosol, resulting in a more reducing environment in the mitochondria (reflecting the high degree to which reactive oxygen species are produced within mitochondria)

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Similar results were reported in studies conducted with Japanese students and Korean children, where higher dietary intake of vitamin E or higher serum alpha-TP levels were associated with improved AD symptoms and lower serum total IgE levels (36, 86)