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While scientists dont know exactly how caffeine works in the brain, the running theory is that it binds to adenosine receptors, preventing a typically adenosine-induced slowdown of wake-promoting brain regions

(PubMed) Fioravanti M, Yanagi M

BO does not stain with Lugols iodine

The ADDF explicitly states: Little human evidence exists for potential side effects. Notably, Selank was removed from Category 2 in September 2024 when nominators withdrew the substance

we don't use alcohol solvents, such as ethanol, that are typically found in liquid supplements

It demonstrated protection against H 2 O 2 -induced neurotoxicity in SH-SY5Y cells (a human neuroblastoma cell line) and neuroinflammation in LPS-stimulated BV-2 cells (a microglial cell line)