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The roles of innate immune cells in liver injury and regeneration

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Additionally, the upregulation of inflammation-related genes, such as IL-6 and TNF-, is associated with the pathological state of depression, suggesting that immune responses play a critical role in its pathogenesis [365, 366]

These molecular interactions facilitate activation of the Ras/RAF/MEK/ERK pathway, quantifiable through phospho-specific antibody detection and real-time PCR analysis of immediate early gene expression profiles

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