In vitro and animal studies suggests that GSH depletion plays an important role in OS-mediated neuronal death and is implicated in neuronal loss in several neurodegenerative diseases, such as Parkinsons disease [16], AD [17], and amyotrophic lateral sclerosis [12], making it a potential therapeutic target to prevent or reduce neurodegeneration
Le glutathion possde de puissantes fonctions antioxydantes, dtoxifiantes et de rgulation immunitaire, qui peuvent neutraliser les radicaux libres, rduire les dommages oxydatifs et aider liminer les toxines du corps
doi: 10.1111/nyas.15299 108 WuQZhangYZhangYXiaCLaiQDongZet al
L.et al (2015)
Complex I obtain the electrons from NADH (NADH-coenzyme Q oxidoreductase) and complex II (succinate-coQ oxidoreductase) from succinate
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