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Combining ferroptosis inducers with immune checkpoint inhibitors, such as anti-CTLA4 (cytotoxic T-lymphocyte associated protein 4), anti-PDCD1/PD-1 (programmed cell death 1), or anti-CD274/PD-L1 (programmed death ligand 1) antibodies, enhances tumor suppression compared to using immune checkpoint inhibitors alone
Overall, the properties of cationic liposomes, such as lipid composition, surface modification, and size, influence their performance and potential applications [79]
Limitations of Current Evidence The absence of large-scale human clinical trials represents the primary evidence gap
L.WibbeltG.HoytJ
In this regard, it is recommended to give up coffee and other products containing caffeine or guarana for a while