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doi: 10.1016/j.cell.2006.01.007 94 MaR-YBlackAQianB-Z
Although metabolite composition found in the stool and urine of study subjects differed significantly across study phases, an abundance of microbial metabolites derived from saccharolysis was significant (Sohn et al., 2024)
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Considering that highly sensitive xCT inhibitors and cystine deprivation can induce ferroptosis, several ferroptosis-inducing agents have been developed [15,35,42]
ADC 2 with PABC linker further enhanced the concentration of MMAE in tumor tissue (87.1 nmol/L) and a 30% tumor regression rate (Figure 10)