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The concentration of these substances directly affects the maturation and quality of oocytes, fertilization, and embryonic development (121)

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In addition, the transcription of this gene would be regulated by factors capable of increasing the levels of cAMP and activating cAMP response-element-binding (CREB)

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In this reaction, vitamin E (-tocopherol-OH) reacts with peroxyl radicals (ROO ) according to the reaction: where -tocopheryl-O is a radical of vitamin E