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In the case of animals inoculated peripherally with scrapie, the agent propagates along peripheral sensory and autonomic nerves in the peritoneum to enter the spinal cord and medulla, and then ascends to invade the brain (Kimberlin and Walker, 1982)

The majority of GSH studies (N = 5, 71%) reported significantly lower plasma levels with increasing age in adults (1885 yrs) (Jones et al., 2002), as well as in old adults relative to (a) young adults by the majority of studies (2/3, 67%) (Giustarini et al., 2006, Yang et al., 1995), and (b) young to middle-aged adults in two studies (Maciejczyk et al., 2019, Samiec et al., 1998)

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149 Transplantation of mitochondria derived from bone marrow mesenchymal stem cells has been shown to promote mitochondrial biogenesis