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Neurotoxicological mechanism of methylmercury induced by low-dose and long-term exposure in mice: Oxidative stress and down-regulated Na+/K(+)-ATPase involved

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Futhermore, GSH was found to reduce ERp57 rapidly at physiological concentrations in vitro , and biotinylated glutathione formed mixed disulphides with ERp57, confirming earlier work showing that glutathione forms a mixed disulphide with ERp57 in intact cells (Fratelli et al , 2002)