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The platform was realized as a multilayer assembly of poly(methyl methacrylate) (PMMA) to structure the medium reservoirs, a poly(ethyleneterephthalate) (PET) foil, a 120-m-thick, patterned double-sided adhesive (DSA) layer to form the vascular microchannel, a porous PET membrane, a second PET layer, and a PMMA layer for forming the rims supporting the hanging drops

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A proposed explanation is that iron is essential for the activity of tyrosine hydroxylase, the enzyme responsible for dopamine synthesis