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All animals were housed in groups of 10 mice per cage in a controlled-temperature/humidity environment (22 1 C, 6070% relative humidity, with wood shaving bedding and nesting material), with a 12 h light/dark cycle (lights on at 7:00 a.m.) and fed with rodent chow (Global Diet 2018, Harlan) and tap water ad libitum

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Moreover, the region of DAT (M 1 - V 15 : MSKSKCSVGPMSSVV) responsible for mediating the interaction with D2R is identical between mice and rats, which the same amino acid sequence was used to synthesized TAT-DAT NT