The mechanism underlying the regulation of glucose homeostasis by E2 signaling is that the ER-expressing neurons in the ventrolateral subdivision of the ventromedial hypothalamic nucleus can sense glucose fluctuations throughout the body and regulate glucose homeostasis [194]
Conversely, HU has been implicated in the progression of renal disease through mechanisms such as tubulointerstitial inflammation, oxidative stress, and endothelial dysfunction
J Vet Med Sci 79:17851790
Several studies have reported an inverse association between dietary choline supplementation and both the incidence and severity of non-alcoholic fatty liver disease (NAFLD) or steatohepatitis (NASH) (159, 160)
While suppression of the proatherogenic T h 1 subset may confer some protection from atherosclerosis in G6PD-d, it is necessary to determine whether the other T cell subsets, particularly the atheroprotective subsets, are similarly affected
Induction of ferroptosis selectively eliminates senescent tubular cells
