A meta-analysis of randomized controlled trials of tianeptine versus SSRI in the short-term treatment of depression
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This has led to ongoing investigation into its broader relationship with healthy ageing, cellular resilience and antioxidant defence systems
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However, studies suggest that supplementing with B12 does not reduce the risk of developing dementia or Alzheimers disease in older adults, or slow its progression
The mitochondrial morphological damage and reduction in cristae induced by ferroptosis inducers were significantly ameliorated by PPARa over-expression, while this protective effect was inhibited by icFSP1 administration or PPARa knockdown (Fig S2a)