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Vitamin D metabolism Vitamin D receptor (VDR) plays a critical role in vitamin D metabolism [104]

The IGF-1 signaling axis is widely studied for its involvement in cellular proliferation, metabolic regulation, tissue growth, and intracellular signaling mechanisms in preclinical research models

LCLs JY and X50-7 were from the European Collection of Authenticated Cell Cultures (ECACC 94022533) and Cellosaurus (RRID:CVCL_8277), respectively

Acknowledgements We appreciate the support from the National Natural Science Foundation of China (82071676, 81703492)

B12 (2 Doses) Vitamin B12 supports nerve health, boosts energy, and aids in red blood cell formation

However, one challenging issue is to retain the biological activities (e.g., antioxidant, anti-microbial, and anti-inflammatory) and functional properties (e.g., emulsifying capacity, water holding capacity, and foaming stability) of PPDP during the extraction and the following processing stages, thus maintaining their health-promoting benefits